Formalisation and methods of analysis of the fast xenobiotic mass transfer in the body

Volume 36 / 2009

Volodymir G. Zinkovsky, Olga V. Zhuk, Micha/l Teodorczyk, Natalia Karpinchik Applicationes Mathematicae 36 (2009), 365-374 MSC: 92C45. DOI: 10.4064/am36-3-8

Abstract

A novel discrimination and regression method for a quantitative determination of the relative efficiency of “fast” distribution processes of xenobiotics is discussed. An integral model-independent method for estimation of equilibrium tissue-to-plasma partition ratios is proposed.

Authors

  • Volodymir G. ZinkovskyDepartment of Biotechnology and Molecular Biology
    University of Opole
    Kominka 4
    45-032 Opole, Poland
  • Olga V. ZhukDepartment of Biotechnology and Molecular Biology
    University of Opole
    Kominka 4
    45-032 Opole, Poland
    e-mail
  • Micha/l TeodorczykDepartment of Biotechnology and Molecular Biology
    University of Opole
    Kominka 4
    45-032 Opole, Poland
    e-mail
  • Natalia KarpinchikDepartment of Biology
    State University of Odessa
    Dvoryanska St. 2
    Odessa 650000, Ukraine
    e-mail

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