A note on control of the false discovery proportion

Volume 36 / 2009

Marcin Dudziński, Konrad Furmańczyk Applicationes Mathematicae 36 (2009), 397-418 MSC: 62J15, 62G10. DOI: 10.4064/am36-4-2

Abstract

We consider the problem of simultaneous testing of a finite number of null hypotheses $H_{i}$, $i=1,\ldots,s$. Starting from the classical paper of Lehmann (1957), it has become a very popular subject of research. In many applications, particularly in molecular biology (see e.g. Dudoit et al. (2003), Pollard et al. (2005)), the number $s$, i.e. the number of tested hypotheses, is large and the popular procedures that control the familywise error rate (FWERM) have small power. Therefore, we are concerned with another error rate measure, called the false discovery proportion (FDP). We prove some theorems about control of the FDP measure. Our results differ from those obtained by Lehmann and Romano (2005).

Authors

  • Marcin DudzińskiFaculty of Applied Informatics and Mathematics
    Department of Applied Mathematics
    Warsaw University of Life Sciences (SGGW)
    Nowoursynowska 159
    02-776 Warszawa, Poland
    e-mail
  • Konrad FurmańczykFaculty of Applied Informatics and Mathematics
    Department of Applied Mathematics
    Warsaw University of Life Sciences (SGGW)
    Nowursynowska 159
    02-776 Warszawa, Poland
    e-mail

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