PDF files of articles are only available for institutions which have paid for the online version upon signing an Institutional User License.

A topological model of site-specific recombination that predicts the knot and link type of DNA products

Volume 100 / 2014

Karin Valencia Banach Center Publications 100 (2014), 223-233 MSC: 57M25; 92B05. DOI: 10.4064/bc100-0-13


This is a short summary of a topological model of site-specific recombination, a cellular reaction that creates knots and links out of circular double stranded DNA molecules. The model is used to predict and characterise the topology of the products of a reaction on double stranded DNA twist knots. It is shown that all such products fall into a small family of Montesinos knots and links, meaning that the knot and link type of possible products is significantly reduced, thus aiding their experimental identification. We also mention direct applications of the model.


  • Karin ValenciaImperial College London
    Department of Mathematics
    South Kensington Campus
    London SW7 2AZ, UK

Search for IMPAN publications

Query phrase too short. Type at least 4 characters.

Rewrite code from the image

Reload image

Reload image